It's the intent and the delivery, I think.
One is intended to be funny and references pop-culture figures.
The other is intended to repeat tired talking points one more time, and is presented in an unimaginative green-to-red panel format.
Pro tip to artist of all stripes: If your ultimate motivation is to preach some tired talking point with your art, it's 99.9% likely you're going to fail.
Commenting on a situation is entirely different than beating an ideological drum, and it's often what separates the greats from the masses of failures.