Otern wrote:Would autists see any benefit in MDMA then? Or is it a real difference when it comes to MDMA on empathy and sympathy?
You want to differentiate between the benefit of a breakthrough intervention facilitated by the drug and the benefit of the effect of the drug while it's active in your bloodstream.
I haven't heard any preliminary evidence of the first kind of drug facilitated interventions on autism. That would be revolutionary.
(I have heard of preliminary evidence in alcoholism, nicotine addiction, PTSD and treatment resistant depression and anxiety though - the alcoholism and nicotine dependence data being the most impressive)
As far as the action of the drug for increasing empathy while intoxicated... I think it would be similar to the psychopath story I told - increasing the potential for empathy but also revealing the barriers to empathy. Autism and Psychopathy are both deficits of the capacity for empathy but stemming from completely different pathways.
If someone with autism had greater empathy while intoxicated with MDMA that would be no different than how most people have more empathy while intoxicated... A time limited effect that probably would become less as the person developed tolerance to the drug and fairly useless clinically.